/* =========================================================
   CLARITÉ RESEARCH — versión corporativa
   Pensada para equipos de site selection / feasibility de
   sponsors y CROs. Cambiá colores y tipografías acá.
   ========================================================= */
:root{
  /* Colores */
  --ink:#0f2742;        /* navy principal: títulos, header oscuro, footer */
  --ink-2:#18375c;      /* navy un poco más claro (hover) */
  --teal:#1f6f68;       /* verde del logo, oscurecido para buen contraste (botones, links) */
  --teal-2:#185a54;     /* hover de botones */
  --teal-soft:#7eccba;  /* verde del logo original (detalles) */
  --mist:#eef5f4;       /* fondo suave de secciones */
  --paper:#ffffff;
  --slate:#586374;      /* texto secundario */
  --text:#1c2733;       /* texto principal */
  --line:#d9e1e6;       /* líneas finas */
  --error:#b42318;

  /* Tipografía */
  --serif:'Source Serif 4',Georgia,serif;
  --sans:'Public Sans',system-ui,sans-serif;

  --wrap:1180px;
  --gutter:24px;
}

*{box-sizing:border-box;margin:0;padding:0}
html{scroll-behavior:smooth}
body{font-family:var(--sans);font-size:17px;line-height:1.65;color:var(--text);background:var(--paper);-webkit-font-smoothing:antialiased}
img{max-width:100%;display:block}
a{color:var(--teal);text-decoration-thickness:1px;text-underline-offset:3px}
a:hover{color:var(--teal-2)}
:focus-visible{outline:3px solid var(--teal-soft);outline-offset:2px;border-radius:2px}
p{margin-bottom:1em}
p:last-child{margin-bottom:0}
.wrap{max-width:var(--wrap);margin:0 auto;padding:0 var(--gutter)}
.skip{position:absolute;left:-999px;top:0;background:var(--ink);color:#fff;padding:10px 16px;z-index:100}
.skip:focus{left:8px;top:8px}

/* ---------- Tipografía ---------- */
h1,h2,h3{font-family:var(--serif);color:var(--ink);font-weight:600;line-height:1.15;letter-spacing:-.01em}
h1{font-size:clamp(36px,5vw,58px)}
h2{font-size:clamp(28px,3.4vw,40px);margin-bottom:.5em}
h3{font-size:22px;margin-bottom:.35em}
h4{font-family:var(--sans);font-size:16px;font-weight:600;color:var(--ink);margin-bottom:.25em}
.lede{font-size:20px;line-height:1.55;color:var(--slate);max-width:36em}
.measure{max-width:38em}
.muted{color:var(--slate)}
.small{font-size:14.5px}

/* ---------- Botones ---------- */
.btn{display:inline-flex;align-items:center;justify-content:center;gap:8px;font-family:var(--sans);font-weight:600;font-size:16px;
  padding:14px 24px;border-radius:4px;text-decoration:none;border:1.5px solid var(--teal);background:var(--teal);color:#fff;cursor:pointer;transition:background .15s,border-color .15s}
.btn:hover{background:var(--teal-2);border-color:var(--teal-2);color:#fff}
.btn.ghost{background:transparent;color:var(--ink);border-color:var(--ink)}
.btn.ghost:hover{background:var(--ink);color:#fff}
.btn.light{background:#fff;color:var(--ink);border-color:#fff}
.btn.light:hover{background:var(--mist);border-color:var(--mist);color:var(--ink)}
.actions{display:flex;flex-wrap:wrap;gap:12px;margin-top:32px}

/* ---------- Header ---------- */
.util{background:var(--ink);color:#c9d6e3;font-size:14px}
.util .wrap{display:flex;justify-content:space-between;align-items:center;min-height:40px;gap:16px}
.util a{color:#fff;text-decoration:none}
.util .lang{display:flex;gap:14px}
.util .lang a[aria-current]{text-decoration:underline;text-underline-offset:4px}

.site-header{background:#fff;border-bottom:1px solid var(--line);position:sticky;top:0;z-index:50}
.site-header .wrap{display:flex;align-items:center;justify-content:space-between;min-height:84px;gap:24px}
.brand img{height:56px;width:auto}
.nav ul{list-style:none;display:flex;align-items:center;gap:4px}
.nav a{display:block;padding:10px 12px;font-size:15px;font-weight:500;color:var(--ink);text-decoration:none;border-bottom:2px solid transparent}
.nav a:hover{color:var(--teal)}
.nav a[aria-current="page"]{border-bottom-color:var(--teal);color:var(--teal)}
.nav .btn{padding:10px 18px;font-size:15px;margin-left:12px;border-bottom-width:1.5px;color:#fff}
.nav .btn[aria-current="page"]{color:#fff;background:var(--teal-2);border-color:var(--teal-2)}
.nav .btn:hover{color:#fff}
.menu-toggle{display:none;background:none;border:1px solid var(--line);border-radius:4px;width:44px;height:44px;font-size:18px;color:var(--ink);cursor:pointer}

/* ---------- Secciones ---------- */
.section{padding:104px 0}
.section.tint{background:var(--mist)}
.section.dark{background:var(--ink);color:#d6e0ea}
.section.dark h2,.section.dark h3{color:#fff}
.section-head{display:grid;grid-template-columns:5fr 7fr;gap:48px;margin-bottom:56px;align-items:end}
.section-head p{color:var(--slate);font-size:18px}
.section.dark .section-head p{color:#b9c7d6}

/* ---------- Home: hero con ficha del sitio ---------- */
.hero{padding:88px 0 96px;background:linear-gradient(180deg,var(--mist) 0%,#fff 100%)}
.hero .wrap{display:grid;grid-template-columns:1.05fr .95fr;gap:72px;align-items:center}
.hero h1{margin-bottom:24px}

.profile{background:#fff;border:1px solid var(--line);border-top:4px solid var(--teal);box-shadow:0 30px 60px -40px rgba(15,39,66,.45)}
.profile header{display:flex;justify-content:space-between;align-items:baseline;padding:22px 28px;border-bottom:1px solid var(--line)}
.profile header h2{font-size:22px;margin:0}
.profile header span{font-size:14px;color:var(--slate)}
.profile dl{display:grid;grid-template-columns:150px 1fr}
.profile dt,.profile dd{padding:15px 28px;border-bottom:1px solid var(--line);font-size:15.5px}
.profile dt{color:var(--slate);padding-right:0}
.profile dd{color:var(--ink);font-weight:500}
.profile dl > :nth-last-child(-n+2){border-bottom:none}
.profile footer{padding:16px 28px;background:var(--mist);font-size:15px;display:flex;justify-content:space-between;gap:16px;flex-wrap:wrap}
.profile footer a{font-weight:600}
@media (prefers-reduced-motion:no-preference){
  .profile dt,.profile dd{animation:row-in .5s ease-out both}
  .profile dt:nth-of-type(1),.profile dd:nth-of-type(1){animation-delay:.10s}
  .profile dt:nth-of-type(2),.profile dd:nth-of-type(2){animation-delay:.18s}
  .profile dt:nth-of-type(3),.profile dd:nth-of-type(3){animation-delay:.26s}
  .profile dt:nth-of-type(4),.profile dd:nth-of-type(4){animation-delay:.34s}
  .profile dt:nth-of-type(5),.profile dd:nth-of-type(5){animation-delay:.42s}
  .profile dt:nth-of-type(6),.profile dd:nth-of-type(6){animation-delay:.50s}
  @keyframes row-in{from{opacity:0;transform:translateY(6px)}to{opacity:1;transform:none}}
}

/* ---------- Banda de foto ---------- */
.photo-band{height:440px;background-size:cover;background-position:center}

/* ---------- Lista de razones (filas con línea) ---------- */
.rows{border-top:1px solid var(--line)}
.row{display:grid;grid-template-columns:5fr 7fr;gap:48px;padding:28px 0;border-bottom:1px solid var(--line)}
.row h3{margin:0;font-size:22px}
.row p{color:var(--slate);margin:0}
.section.dark .rows,.section.dark .row{border-color:rgba(255,255,255,.14)}
.section.dark .row p{color:#b9c7d6}

/* ---------- Áreas terapéuticas ---------- */
.areas{display:grid;grid-template-columns:repeat(4,1fr);border-top:2px solid var(--ink)}
.area{padding:28px 28px 8px 0}
.area + .area{padding-left:28px;border-left:1px solid var(--line)}
.area i{font-size:22px;color:var(--teal);margin-bottom:18px;display:block}
.area p{color:var(--slate);font-size:15.5px}

/* ---------- Split imagen + texto ---------- */
.split{display:grid;grid-template-columns:1fr 1fr;gap:72px;align-items:center}
.split.reverse > :first-child{order:2}
.split img{width:100%;aspect-ratio:4/3;object-fit:cover}
.split .tall{aspect-ratio:4/5}

/* ---------- Cita / investigadora ---------- */
.pi{display:grid;grid-template-columns:auto 1fr;gap:32px;align-items:start;padding:40px;border:1px solid var(--line);background:#fff}
.pi .mono{width:72px;height:72px;border-radius:50%;background:var(--ink);color:#fff;font-family:var(--serif);font-size:26px;display:flex;align-items:center;justify-content:center}
.pi blockquote{font-family:var(--serif);font-size:22px;line-height:1.45;color:var(--ink);margin-bottom:16px}
.pi cite{font-style:normal;color:var(--slate);font-size:15px}
.pi cite strong{color:var(--ink);font-weight:600}

/* ---------- Bloque de cierre (CTA doble) ---------- */
.paths{display:grid;grid-template-columns:1fr 1fr;border-top:1px solid rgba(255,255,255,.14)}
.path{padding:48px 48px 8px 0}
.path + .path{padding-left:48px;border-left:1px solid rgba(255,255,255,.14)}
.path p{color:#b9c7d6;margin-bottom:24px}

/* ---------- Encabezado de páginas internas ---------- */
.page-head{background:var(--mist);padding:80px 0 72px;border-bottom:1px solid var(--line)}
.page-head .wrap{display:grid;grid-template-columns:7fr 5fr;gap:48px;align-items:end}
.page-head h1{font-size:clamp(34px,4.4vw,52px)}
.page-head p{color:var(--slate);font-size:19px}
.crumbs{font-size:14px;color:var(--slate);margin-bottom:20px}
.crumbs a{color:var(--slate)}

/* ---------- Proceso (secuencia real del ensayo) ---------- */
.steps{list-style:none;display:grid;grid-template-columns:repeat(4,1fr);gap:0;counter-reset:s}
.steps li{counter-increment:s;padding:0 28px 0 0;position:relative}
.steps li + li{padding-left:28px;border-left:1px solid var(--line)}
.steps li::before{content:counter(s);display:flex;width:36px;height:36px;border-radius:50%;border:1.5px solid var(--teal);color:var(--teal);
  align-items:center;justify-content:center;font-weight:600;font-size:15px;margin-bottom:20px}
.steps p{color:var(--slate);font-size:15.5px}

/* ---------- Lista de capacidades ---------- */
.checks{list-style:none;columns:2;column-gap:48px}
.checks li{break-inside:avoid;padding:14px 0 14px 32px;border-bottom:1px solid var(--line);position:relative}
.checks li::before{content:"\f00c";font-family:"Font Awesome 6 Free";font-weight:900;position:absolute;left:0;top:15px;color:var(--teal);font-size:14px}
.section.dark .checks li{border-color:rgba(255,255,255,.14)}
.section.dark .checks li::before{color:var(--teal-soft)}

/* ---------- Valores ---------- */
.values{display:grid;grid-template-columns:repeat(5,1fr);border-top:2px solid var(--ink)}
.values div{padding:24px 20px 0 0}
.values div + div{padding-left:20px;border-left:1px solid var(--line)}
.values p{color:var(--slate);font-size:15px}

/* ---------- Preguntas frecuentes ---------- */
.faq{border-top:1px solid var(--line)}
.faq details{border-bottom:1px solid var(--line)}
.faq summary{list-style:none;cursor:pointer;padding:22px 40px 22px 0;font-family:var(--serif);font-size:21px;color:var(--ink);position:relative}
.faq summary::-webkit-details-marker{display:none}
.faq summary::after{content:"+";position:absolute;right:4px;top:18px;font-family:var(--sans);font-size:26px;color:var(--teal);transition:transform .2s}
.faq details[open] summary::after{transform:rotate(45deg)}
.faq details > div{padding:0 0 24px;color:var(--slate);max-width:44em}

/* ---------- Formularios ---------- */
.form-panel{background:#fff;border:1px solid var(--line);padding:40px}
.form-grid{display:grid;grid-template-columns:1fr 1fr;gap:20px 24px}
.form-grid .full{grid-column:1/-1}
.field label,.field legend{display:block;font-size:15px;font-weight:600;color:var(--ink);margin-bottom:6px}
.field .opt{font-weight:400;color:var(--slate)}
.field input,.field select,.field textarea{width:100%;font:inherit;font-size:16px;color:var(--text);background:#fff;border:1px solid #b9c4cd;border-radius:4px;padding:12px 14px}
.field textarea{min-height:130px;resize:vertical}
.field input:focus,.field select:focus,.field textarea:focus{outline:none;border-color:var(--teal);box-shadow:0 0 0 3px rgba(31,111,104,.18)}
.field .hint{font-size:13.5px;color:var(--slate);margin-top:4px;display:flex;justify-content:space-between}
.field fieldset{border:none}
.choice{display:flex;gap:24px;flex-wrap:wrap}
.choice label{display:flex;align-items:center;gap:8px;font-weight:400;margin:0}
.choice input{width:18px;height:18px;accent-color:var(--teal)}
.consent label{display:flex;gap:14px;align-items:flex-start;font-weight:400;font-size:15px;line-height:1.6;color:var(--text);margin:4px 0 0}
.consent input[type=checkbox]{flex:0 0 22px;width:22px;height:22px;margin-top:2px;accent-color:var(--teal);cursor:pointer}
.consent em{color:var(--slate)}
.field .err{display:none;color:var(--error);font-size:13.5px;margin-top:4px}
.field.invalid input,.field.invalid select,.field.invalid textarea{border-color:var(--error)}
.field.invalid .err{display:block}
.form-foot{display:flex;justify-content:space-between;align-items:center;gap:16px;flex-wrap:wrap;margin-top:28px}
.form-foot p{font-size:14px;color:var(--slate);max-width:30em;margin:0}
.form-ok{display:none;margin-top:20px;padding:16px 18px;background:var(--mist);border-left:3px solid var(--teal);color:var(--ink)}
.form-ok.show{display:block}
.form-error{display:none;margin-top:20px;padding:16px 18px;background:#fdf1f0;border-left:3px solid var(--error);color:var(--error)}
.form-error.show{display:block}
.btn:disabled{opacity:.6;cursor:wait}

/* ---------- Equipo (página Nosotros) ---------- */
.people{display:grid;grid-template-columns:1fr 1fr;gap:40px}
.person{background:#fff;border:1px solid var(--line);display:grid;grid-template-columns:200px 1fr;gap:28px;padding:28px;align-items:start}
.person img{width:100%;aspect-ratio:4/5;object-fit:cover;object-position:center top;filter:grayscale(1)}
.person h3{margin-bottom:4px}
.person .role{color:var(--teal);font-weight:600;font-size:15px;margin-bottom:14px}
.person p{color:var(--slate);font-size:15.5px}
@media (max-width:1080px){.people{grid-template-columns:1fr}}
@media (max-width:600px){.person{grid-template-columns:1fr;padding:22px}.person img{max-width:260px}}

/* Contacto */
.contact-grid{display:grid;grid-template-columns:4fr 7fr;gap:64px;align-items:start}
.details dt{font-size:14.5px;color:var(--slate);margin-top:22px}
.details dt:first-child{margin-top:0}
.details dd{font-size:18px;color:var(--ink)}
.details dd a{color:var(--ink);text-decoration:none}
.details dd a:hover{color:var(--teal)}
.map iframe{width:100%;height:260px;border:0;margin-top:32px;filter:grayscale(.3)}

/* ---------- Footer ---------- */
.footer{background:var(--ink);color:#b9c7d6;padding:72px 0 0;font-size:15.5px}
.footer .cols{display:grid;grid-template-columns:4fr 2fr 2fr 3fr;gap:40px;padding-bottom:56px}
.footer .logo{background:#fff;padding:10px 14px;display:inline-block;margin-bottom:20px}
.footer .logo img{height:44px}
.footer h4{color:#fff;font-size:15px;margin-bottom:14px}
.footer ul{list-style:none}
.footer li{margin-bottom:8px}
.footer a{color:#dce5ee;text-decoration:none}
.footer a:hover{color:#fff;text-decoration:underline}
.footer .base{border-top:1px solid rgba(255,255,255,.14);padding:22px 0;display:flex;justify-content:flex-start;gap:16px 40px;flex-wrap:wrap;font-size:14px}
.footer .social{display:flex;gap:12px;margin-top:22px}
.footer .social a{width:42px;height:42px;border-radius:50%;border:1px solid rgba(255,255,255,.3);display:inline-flex;align-items:center;justify-content:center;
  color:#fff;font-size:17px;text-decoration:none;transition:background .15s,border-color .15s,color .15s}
.footer .social a:hover{background:var(--teal-soft);border-color:var(--teal-soft);color:var(--ink);text-decoration:none}

/* ---------- Responsive ---------- */
@media (max-width:1080px){
  .nav ul{gap:0}
  .nav a{padding:10px 8px;font-size:14px}
  .hero .wrap{grid-template-columns:1fr;gap:48px}
  .areas{grid-template-columns:1fr 1fr}
  .area:nth-child(3){padding-left:0;border-left:none}
  .area:nth-child(n+3){border-top:1px solid var(--line)}
  .values{grid-template-columns:1fr 1fr 1fr}
  .values div:nth-child(4){padding-left:0;border-left:none}
  .values div:nth-child(n+4){border-top:1px solid var(--line);margin-top:24px}
}
@media (max-width:900px){
  .menu-toggle{display:block}
  .nav{display:none;position:absolute;top:100%;left:0;right:0;background:#fff;border-bottom:1px solid var(--line);padding:8px var(--gutter) 20px}
  .nav.open{display:block}
  .nav ul{flex-direction:column;align-items:stretch}
  .nav a{padding:14px 0;border-bottom:1px solid var(--line);font-size:16px}
  .nav a[aria-current="page"]{border-bottom-color:var(--line)}
  .nav .btn{margin:16px 0 0}
  .section{padding:72px 0}
  .section-head,.page-head .wrap,.split,.contact-grid,.paths{grid-template-columns:1fr;gap:28px}
  .split.reverse > :first-child{order:0}
  .row{grid-template-columns:1fr;gap:8px}
  .steps{grid-template-columns:1fr 1fr;row-gap:40px}
  .steps li:nth-child(3){padding-left:0;border-left:none}
  .path,.path + .path{padding:40px 0 0;border-left:none}
  .path + .path{border-top:1px solid rgba(255,255,255,.14);margin-top:40px}
  .footer .cols{grid-template-columns:1fr 1fr}
  .photo-band{height:280px}
}
@media (max-width:600px){
  body{font-size:16px}
  .brand img{height:44px}
  .util .tagline{display:none}
  .profile dl{grid-template-columns:1fr}
  .profile dt{padding-bottom:0;border-bottom:none}
  .profile dd{padding-top:2px}
  .profile header,.profile dt,.profile dd,.profile footer{padding-left:20px;padding-right:20px}
  .areas,.values,.steps{grid-template-columns:1fr}
  .area,.area + .area,.values div,.values div + div,.steps li,.steps li + li{padding-left:0;border-left:none}
  .area + .area,.values div + div{border-top:1px solid var(--line)}
  .checks{columns:1}
  .form-grid{grid-template-columns:1fr}
  .form-panel{padding:24px 20px}
  .pi{grid-template-columns:1fr;padding:28px 22px}
  .footer .cols{grid-template-columns:1fr}
}
.nw{white-space:nowrap}

/* ---------- Páginas legales (Privacy Policy / Terms) ---------- */
.effective{display:inline-block;margin-top:10px;font-size:15px;color:var(--ink);font-weight:600}
mark.pending{background:#fff3cd;color:#7a5b00;padding:0 4px}
.legal-layout{display:grid;grid-template-columns:260px 1fr;gap:64px;align-items:start}
.toc{position:sticky;top:108px;font-size:14.5px;border-left:2px solid var(--line);padding-left:18px}
.toc-title{font-weight:600;color:var(--ink);margin-bottom:10px}
.toc ol{list-style:none}
.toc li{margin-bottom:8px;line-height:1.4}
.toc a{color:var(--slate);text-decoration:none}
.toc a:hover{color:var(--teal);text-decoration:underline}
.legal{max-width:44em}
.legal h2{font-size:28px;margin:56px 0 16px;padding-top:28px;border-top:1px solid var(--line);scroll-margin-top:110px}
.legal h2:first-child{margin-top:0;padding-top:0;border-top:none}
.legal h3{font-family:var(--sans);font-size:18px;font-weight:600;margin:28px 0 8px}
.legal p,.legal address{color:var(--text);margin-bottom:14px}
.legal address{font-style:normal;background:var(--mist);border-left:3px solid var(--teal);padding:16px 20px;line-height:1.8}
.legal .signoff{margin-top:40px;color:var(--slate)}
.legal .related{margin-top:48px;padding-top:24px;border-top:1px solid var(--line);color:var(--slate)}
.footer .legal-links{display:flex;gap:20px;flex-wrap:wrap}
@media (max-width:900px){
  .legal-layout{grid-template-columns:1fr;gap:32px}
  .toc{position:static;border-left:none;padding:20px;background:var(--mist)}
}

/* ---------- Selector de idioma con bandera ---------- */
.util .lang{align-items:center}
.util .flag{display:inline-flex;align-items:center;padding:4px;border-radius:3px;line-height:0}
.util .flag img{width:24px;height:16px;object-fit:cover;border-radius:2px;box-shadow:0 0 0 1px rgba(255,255,255,.45)}
.util .flag:hover img{box-shadow:0 0 0 2px #fff}